The Journal of Investigational Allergology and Clinical Immunology (J Investig Allergol Clin Immunol) provides an attractive and very active forum for basic and clinical research in allergology and clinical immunology. The journal publishes original works, reviews, short communications and opinions. It is the Official Journal ofthe Spanish Society of Allergology and Clinical Immunology (SEAIC). The journal will appear bimonthly (6 issues each year). The peer-review system, based on a team of internationally renowned and committed editors, guarantees the scientific quality of the papers.

Current ISSUE


2025; volume 35, Issue 1
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Review

Phenotyping Asthma Exacerbations: One Step Further in the Management of Severe Asthma
Ojanguren I, Quirce S, Bobolea I, Pérez de Llano L, del Pozo V
[summary] [PDF full-Text] Continual Medical Education ( credits)

How Far Are We From Achieving Delabeling of False Penicillin/ß-Lactam Allergy Alerts? A Population Problem
Tejedor-Alonso MA, Perez-Encinas M, Sanz Márquez S, Martinez Simon JJ, Moreno-Nuñez L, Gonzalez-Moreno A, Macias-Iglesias J, Rosado-Ingelmo A
[summary] [PDF full-Text]

Original Articles

LAD2 Mast Cell Activation Test Associates With the Reaction Severity and Diagnoses BAT Nonresponders in Hymenoptera Venom Allergy
Koren A, Dejanovic L, Kopac P, Erzen R, Bajrovic N, Zidarn M, Korosec P
[summary] [PDF full-Text] [Supplemental Materials]

Sunflower (Helianthus annuus) Seed Allergy
Galleani C, Diéguez MC, Cabanillas B, Martín-Arriscado Arroba C, Enríquez-Matas A, Crespo JF
[summary] [PDF full-Text]

Factors Affecting the Safety and Effectiveness of Venom Immunotherapy
Arzt-Gradwohl L, Herzog SA, Aberer W, Alfaya Arias T, Antolín-Amérigo D, Bonadonna P, Boni E, Bożek A, Chełmińska M, Ebner B, Frelih N, Gawlik R, Gelincik A, Hawranek T, Hoetzenecker W, Jiménez Blanco A, Kita K, Kendirlinan R, Košnik M, Laipold K, Lang R, Marchi F, Mauro M, Nittner-Marszalska M, Poziomkowska-Gęsicka I, Pravettoni V, Preziosi D, Quercia O, Reider N, Rosiek-Biegus M, Ruiz-Leon B, Schrautzer C, Serrano P, Sin A, Sin BA, Stoevesandt J, Trautmann A, Vachová M, Sturm GJ
[summary] [PDF full-Text] [Supplemental Materials]

Practitioner's Corner

Short Communications

Characteristics of Asthma Patients Admitted to the Intensive Care Unit of a Tertiary University Hospital in Madrid, Spain: A 5-Year Experience
Lozano-Espinosa M, Rodríguez-Otero N, Antolín-Amérigo D, Gordo Vidal F, Muriel A, de Pablo R, Quirce S
[summary] [PDF full-Text] [Supplemental Materials]

Stability of Asthma Phenotypes in the Spanish Cohort of the MEGA Project
Rial MJ, Betancor D, Cañas JA, Olaguibel JM, Rodrigo-Muñoz JM, Alvarez-Puebla MJ, Arismendi E, Barroso B, Bobolea I, Cárdaba B, Cruz MJ, Curto E, Del Pozo V, Domínguez-Ortega J, Garcia de la Fuente A, González-Barcala FJ, Luna-Porta JA, Martínez-Rivera C, Mullol J, Muñoz X, Picado C, Plaza V, Quirce S, Soto-Retes L, Valverde-Monge M, Sastre J
[summary] [PDF full-Text] [Supplemental Materials]

A Fully Human Monoclonal Antibody Isolated From a Beekeeper Targets the Immunodominant IgE Epitope of Api m 10
Lund A, Dorn B, Jakob T, Christensen LH, Jabs F, Spillner E
[summary] [PDF full-Text] [Supplemental Materials]

Case Reports

Nonmandatory Labeled Legumes Are an Emergent Safety Concern: An Illustrative Case Report
Vera-Berrios RN, Uriarte Vega L, Marco-Martín G, Fernández-Rivas M
[summary] [PDF full-Text] [Supplemental Materials]

Exercise-Dependent Codfish Allergy due to Tropomyosin
Faihs V, Kugler C, Eberlein B, Bent R, Darsow U, Boehm TM, Hilger C, Biedermann T, Kuehn A, Brockow K
[summary] [PDF full-Text] [Supplemental Materials]

Unveiling the Immunological Mechanism Underlying a Cutaneous Adverse Reaction to Enfortumab Vedotin: A Case Report Based on the Lymphocyte Transformation Test
Gutiérrez-Canales P, Fernández-Lozano C, Alba-Pérez V, Ruiz-Granados A, Díaz-Montalvo L, Martínez-Botas J, Solano-Solares E
[summary] [PDF full-Text]

Allergy to Red Mullet and Sea Bass: Two Newly Identified Red Mullet Allergens
Escalante-Carrero MD, Renilla-Arroyo JM, Fernández C, Martínez-Botas J, Antolín-Amérigo D, De la Hoz-Caballer B
[summary] [PDF full-Text] [Supplemental Materials]

Are Biosimilars of Biologics the Same as the Reference Drug in Terms of Allergy? Selective Allergy to Tocilizumab Biosimilar
Betancor D, Gómez-López A, Barroso B, Valverde-Monge M, Cañas JA, Rodrigo-Muñoz JM, del Pozo V, Sastre J
[summary] [PDF full-Text] [Supplemental Materials]

Two Nonimmediate Reactions to Oxaliplatin and Docetaxel Confirmed by Lymphocyte Transformation Test and Treated With Successful Rapid Desensitization Procedures
Berges-Gimeno MP, Barra-Castro A, Fernandez- Lozano C, Solano-Solares E, Martinez-Jañez N, Pueyo-Lopez C, Martínez-Botas J
[summary] [PDF full-Text]

Ozenoxacin-Induced Contact Dermatitis With Tolerance to Ciprofloxacin
Otero-Fernández MN, Laffond-Yges E, Castillo-Loja RM, Cabrera-Núñez A, Mazoteras-Martínez ME, Muñoz-Bellido FJ, Dávila I
[summary] [PDF full-Text]

Armelline Almond Allergy: The First Reported Case
Alessi L, Cirrincione S, Aiuto B, Gosso E, Cavallarin L, Giuffrida MG, Monti G, Lamberti C
[summary] [PDF full-Text] [Supplemental Materials]