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Case Report
 

Simultaneous Allergy to Vine Pollen and Grape
 

P Mur,1 F Feo Brito,2 B Bartolomé,3 PA Galindo,2 E Gómez,2 J Borja,2 A Alonso2

1 Allergy Unit. Hospital Santa Bárbara, Puertollano, Ciudad Real, Spain
2 Allergy Section, Hospital Complex, Ciudad Real, Spain
3 R & D Department, Bial-Arístegui, Bilbao, Spain

J Investig Allergol Clin Immunol 2006; Vol. 16(4): 271-273
 

 Abstract


We report the case of an 18-year-old female student suffering from seasonal rhinoconjunctivitis with sensitization to pollens from vine and also from grass, olive, and Chenopodiaceae plants who had recently developed episodes of itching, maculopapular rash, and facial angioedema after eating grapes. Testing revealed positive reactions to vine pollen and grapes, and specific IgE were found for both allergens. Immunoblotting and inhibition assays revealed cross-reactivity between the allergenic structures of vine pollen and grape fruit and also among botanically unrelated pollens.

Key words: Food allergy. Fruit allergy. Grape. Vine pollen allergy. Immunoblotting.