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A Valero,1,2 E Baró,3
J Sastre,4 AM Navarro-Pulido,5 I
Izquierdo,6 E Martí-Guadaño,7 M
Ferrer,8,9 I Dávila,10 A del
Cuvillo,11 C Colas,12 I Antepara,13
J Alonso,8,9 J Mullol2,14 |
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1 Allergy Unit, Pneumology and Allergy
Department, Hospital Clínic, Barcelona, Spain (Study
Coordinator)
2 CIBER in Respiratory Diseases (CIBERES), Spain
3 3D Health Research, Barcelona, Epidemiology
Department, Spain
4 Allergology Department, Jiménez Díaz Foundation,
Madrid, Spain
5 Allergology Unit, El Tomillar Hospital, Dos Hermanas,
Sevilla, Spain
6 J Uriach & Co, Barcelona, Spain
7 Hospital San Pere Claver Foundation, Barcelona, Spain
8 Health Services Research Unit, (IMIM-Hospital del
Mar), Barcelona, Spain
9 CIBER in Epidemiology and Public Health (CIBERESP),
Spain
10 Allergology Department, Hospital Clínico, Salamanca,
Spain
11 Allergology Department, Dr Lobatón Clinic, Cadiz,
Spain
12 Allergology Department, Hospital Clínico
Universitario Lozano Blesa, Zaragoza, Spain
13 Allergology Department, Basurto Hospital, Bilbao,
Spain
14 Rhinology Unit, Otorhinolaryngology Service, Hospital
Clínic, Barcelona, Spain |
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Abstract |
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Objective:
ESPRINT-15 is a
specific, short-form
instrument to
measure
health-related
quality of life in
adults suffering
from allergic
rhinitis.
The aim of this
study was to obtain
reference values in
order to improve its
interpretability.
Methods:
ESPRINT-15 was
administered to a
representative
sample of Spanish
adults with allergic
rhinitis. Means and
percentiles were
obtained, taking
into account the
kind of rhinitis
(persistent/intermittent)
and symptom severity
(very
mild/mild/moderate/severe).
Results: A
total of 2756
patients
participated in the
study. Mean (SD)
scores were
significantly lower
(better) for men
than for women (2.2
[1.4] vs 2.4 [1.4],
P<.001, effect size
[ES]≡0.15).
Patients with
intermittent
rhinitisshowed
better scores than
patients with
persistent rhinitis
(2.1 [1.4] vs. 2.5
[1.4], P<.001, ES≡0.21).
Mean (SD) scores
were higher (worse)
when severity of
symptoms increased,
ranging from 0.9
(0.9) (very mild) to
3.7 (1.0) (severe)
(ES≡1.0
between each
consecutive group of
symptom severity).
Conclusions:
The magnitude of the
differences found
among groups of
patients reinforces
the usefulness of
providing reference
values stratified by
gender, type of
allergic rhinitis,
and symptom
severity. The
percentiles obtained
can be used in
clinical practice to
evaluate individual
scores, and assign
the patient to the
corresponding
reference group.
Key words:
Allergic rhinitis.
Adults. Specific
questionnaire.
Health perception.
Reference values.
Spanish version.
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