|
Document Written by the Drug
Allergy Committee of the Spanish Society of Allergology
and Clinical Immunology (Sociedad Española de
Alergología e Inmunología Clínica, SEAIC)
MT Audicana Berasategui,1 MJ Barasona
Villarejo,2 M Corominas Sánchez,3
M De Barrio Fernández,4 MC García Avilés,5
JC García Robaina,6 G Gastaminza Lasarte,7
JJ Laguna Martínez,8 T Lobera Labairu,9
M López San Martín,10 J Martín Lázaro,11
E Moreno Rodilla,12 N Ortega Rodríguez,13
MJ Torres Jaén14 |
|
1Hospital Santiago Apóstol, Vitoria,
Spain
2Hospital Universitario Reina Sofía, Córdoba, Spain
3Hospital Universitari de Bellvitge, LHospitalet del
Llobregat, Barcelona, Spain
4Hospital General Universitario Gregorio Marañon,
Madrid, Spain
5Hospital de Torrevieja, Alicante, Spain
6Hospital Universitario Nuestra Señora de la Candelaria,
Santa Cruz de Tenerife, Spain
7Clínica Universidad de Navarra, Pamplona, Spain
8Hospital Central de la Cruz Roja, Madrid, Spain
9Hospital San Pedro, Logroño, Spain
10Hospital Universitario Puerta de Hierro, Majadahonda,
Spain
11Hospital Arquitecto Marcide, La Coruña, Spain
12Hospital Universitario, Salamanca, Spain
13Hospital General de Gran Canaria Dr. Negrín, Las
Palmas, Spain
14Hospital Civil, Málaga, Spain |
|
Abstract |
|
The Drug Allergy
Committee of the
Spanish Society of
Allergology and
Clinical Immunology
reviewed the
allergenic potential
of several
substances of food
origin that are
found in the
composition of some
drugs. Despite
recent legislation
on labeling, many
labels do not
clearly state
whether the drug
contains raw
material (active
ingredients,
excipient, or other
manufacturing
intermediate) with
an origin in any of
the substances in
the list of the 14
groups of food
allergens that are
subject to mandatory
declaration. The
objective of
legislation is that
the drug package,
the Summary of
Product
Characteristics, and
the patient
information leafl et
clearly state the
food content in
order to improve the
safety of allergic
patients.
Therefore, any food
or allergen
derivative that must
be declared should
be clearly stated on
the drug label. Of
all the evaluated
products, egg and
milk derivatives are
the most frequently
discussed in
literature reviews.
The natural or
synthetic origin of
potentially
allergenic
substances such as
lysozyme, casein,
lactose, albumin,
phosphatide, and
aromatic essences
should be clearly
stated.
Providing this
information has 2
clear advantages.
First, allergic
reactions to drugs
in patients with
food allergy could
be avoided (if the
substances have a
natural origin).
Second, prescription
would improve by not
restricting drugs
containing synthetic
substances (which do
not usually induce
allergic reactions).
Key words: Food
allergy. Drug
allergy. Additive.
Egg. Milk.
|
|
|
|
| |
|
|
