Practitioner's Corner

Severe Primary Antibody Deficiency Due to a Novel Mutation of μ Heavy Chain

I Mohammadzadeh,¹ M Yeganeh,² A Aghamohammadi,³ N Parvaneh,³ N Behniafard,³ H Abolhassani,³ F Tabassomi,³ M
Hemmat,³ H Kanegane,⁴ T Miyawaki,⁴ O Ohara,⁵ N Rezaei^3,6

1Department of Pediatrics, Amirkola Hospital, Babol University of Medical Sciences, Babol, Iran
2Division of Immunology, Department of Pediatrics, Faculty of Medicine, University of Sherbrooke, Centre de Recherche
Clinique Etienne Le-Bel, Centre Hopitalier Universitaire de Sherbrooke, Sherbrooke, Canada
3Research Center for Immunodefi ciencies, Children’s Medical Center, Tehran University of Medical Sciences, Tehran, Iran
4Department of Pediatrics, Faculty of Medicine, Toyama Medical and Pharmaceutical University, Toyama, Japan
5Department of Human Genome Research, Kazusa DNA Research Institute, Chiba, Japan
6Molecular Immunology Research Center; and Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran

J Investig Allergol Clin Immunol 2012; Vol. 22(1): 63-79