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Remifentanil-Induced Symmetric Drug-Related Intertriginous and Flexural Exanthema: A Diagnostic Challenge in an Intensive Care Patient

Martins JF1*, Alen Coutinho I2,3*, Castro M4, Carvalho J2, Faria C5, Sousa E1, Martins P1,6


1
Intensive Medicine Department, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal
2Allergy and Clinical Immunology Department, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal
3Immunology Department, Faculty of Medicine, University of Coimbra, Coimbra, Portugal
4Anesthesiology Department, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal
5Histopathology Department, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal
6Faculty of Medicine, University of Coimbra, Coimbra, Portugal
*Both authors contributed equally to this work

J Investig Allergol Clin Immunol 2022; Vol 32(5) : 399-401
doi: 10.18176/jiaci.0764

Key words: Delayed hypersensitivity reaction, Lymphocyte transformation test, Patch testing, Remifentanil, Symmetric drug-related intertriginous and flexural exanthema (SDRIFE)

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